2-Aminoethyl diphenylborinate

国际站：2-Aminoethyl diphenylborinate

CAS：524-95-8

品牌：MedChemExpress (MCE)

存储条件：Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.

生物活性：2-Aminoethyl diphenylborinate (2-APB) 是一种细胞渗透性 IP3R 抑制剂。 2-Aminoethyl diphenylborinate 还抑制 store-operated Ca²⁺ (SOC) 通道并激活一些 TRP 通道（V1、V2 和 V3） ^[1][2][3]。

参考文献：[1]. Ma S, et al. Effect of Wilforine on the Calcium Signaling Pathway in Mythimna separata Walker MyocytesUsing the Calcium Imaging Technique. J Agric Food Chem. 2019 Nov 27.[2]. Boyacı MG, et al. Effects of 2-Aminoethyl Diphenylborinate, a Modulator of Transient Receptor Potential and OraiChannels in Subarachnoid Hemorrhage: An Experimental Study.[3]. Takahashi K, et al. Molecular mechanism of 2-APB-induced Ca²⁺ influx in external acidification in PC12. Exp Cell Res. 2014 May 1;323(2):337-45.