在生物信息学的江湖里，大侠Heng Li 暑期发文一篇。且看摘要：

1. Heng Li

+Author Affiliations

1. Medical Population Genetics Program, Broad Institute, 75 Ames Street, Cambridge, MA 02142, USA

• Received June 2, 2014.

• Revision received July 15, 2014.

• Accepted August 4, 2014.

Summary: We present a new method to incrementally construct the FM-index for both short and long sequence reads, up to the size of a genome. It is the first algorithm that can build the index while implicitly sorting the sequences in the reverse (complement) lexicographical order without a separate sorting step. The implementation is among the fastest for indexing short reads and the only one that practically works for reads of averaged kilobases in length.

Availability and implementation: https://github.com/lh3/ropebwt2

Contact: hengli@broadinstitute.org

• © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

由于跟大侠段数差得太远，不敢对其武功的精妙之处妄加品评，但其气场还是透过屏幕扑面而来。大侠文风和其系列软件（BWA，Samtools等）一样简洁有力；两个月的审稿时间充分说明其出招快、准、狠；单一作者更有一种独来独往的萧瑟悲凉之感；而全文使用We做主语更显示了一种皇室气度（参见Royal We）。

感慨一番，以自勉。